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Publications de l’équipe Ingénierie moléculaire et glycobiologie


Coppin L, Vincent A, Frénois F, Duchêne B, Lahdaoui F, Stechly L, Renaud F, Villenet C, Seuningen IV, Leteurtre E, Dion J, Grandjean C, Poirier F, Figeac M, Delacour D, Porchet N, Pigny P. Galectin-3 is a non-classic RNA binding protein that stabilizes the mucin MUC4 mRNA in the cytoplasm of cancer cells. Sci Rep . 2017 Mar 6 ;7:43927. doi : 10.1038/srep43927


Forato F, Liu H, Benoit R, Fayon F, Charlier C, Fateh A, Defontaine A, Tellier C, Talham D R, Queffelec C, Bujoli, Bruno. Comparison of Zirconium Phosphonate-Modified Surfaces for Immobilizing Phosphopeptides and Phosphate-Tagged Proteins. Langmuir : the ACS journal of surfaces and colloids . 2016, 32(22):5480-5490. doi : 10.1021/acs.langmuir.6b01020

Goux M, Fateh A, Defontaine, Cinier M, Tellier C. In vivo phosphorylation of a peptide tag for protein purification. Biotechnol Lett . 2016, doi : 10.1007/s10529-016-2040-4


Saumonneau A, Champion E, Peltier-Pain P, Molnar-Gabor D, Hendrickx J, Tran V, Hederos M, Dekany G, Tellier C. Design of an alpha-L-transfucosidase for the synthesis of fucosylated HMOs. Glycobiology . 2015, doi : 10.1093/glycob/cwv099

Cabezas Y, Legentil L, Robert-Gangneux F, Daligault F, Belaz S, Nugier-Chauvin C, Tranchimand S, Tellier C, Gangneux J-P, Ferrieres V. Leishmania cell wall as a potent target for antiparasitic drugs. A focus on the glycoconjugates. Org Biomol Chem. 2015, 13:8393-8404 (IF 3.568)

Teze D, Daligault F, Ferrières V, Sanejouand Y-H, Tellier C. Semi-rational approach for converting a GH36 α-glycosidase into an α-transglycosidase. Glycobiology. 2015, 25:420‑427 (IF 3.537)

André-Miral C, Koné FM, Solleux C, Grandjean C, Dion M, Tran V, Tellier C. De novo design of a trans-β-N-acetylglucosaminidase activity from a GH1 β-glycosidase by mechanism engineering. Glycobiology. 2015, 25:394-402 (IF 3.537)

Advedissian T, Deshayes F, Poirier F, Grandjean C, Viguier M. Les galectines, des lectines pas comme les autres. Med Sci (Paris). 2015, 31:499-505 (IF 0.519)

Brissonnet Y, Ladevèze S, Tezé D, Fabre E, Deniaud D, Daligault F, Tellier C, Sestak S, Remaud-Simeon M, Potocki-Veronese G, Gouin SG. Polymeric iminosugars improve the activity of carbohydrate-processing enzymes. Bioconjug Chem. 2015, 26:766‑72 (IF 4.58)

Arab-Jaziri F, Bissaro B, Tellier C, Dion M, Fauré R, O’Donohue MJ. Enhancing the chemoenzymatic synthesis of arabinosylated xylo-oligosaccharides by GH51 α-l-arabinofuranosidase. Carbohydr Res. 2015, 401:64‑72 (IF 2.044)


Wade WF, King RG, Grandjean C, Wade T K, Justement LB. Murine marginal zone B cells play a role in Vibrio cholerae LPS antibody responses. Pathog Dis. 2014, 70:153–157 (IF 2.554)

Teze D, Hendrickx J, Czjzek M, Ropartz D, Sanejouand Y-H, Tran V, Tellier C, Dion M.. Semi-rational approach for converting a GH1 β-glycosidase into a β-transglycosidase. Protein Eng Des Sel. 2014, 27:13‑9 (IF 2.588)

Milhomme O, Grandjean C. Synthetic efforts towards glycoconjugate-based vaccines active against Anthrax. Curr Org Chem. 2014, 18:291–311 (IF 3.039)

Suleman M, Gangneux J-P, Legentil L, Belaz S, Cabezas Y, Manuel C, Dureau R, Sergent O, Burel A, Daligault F, Ferrières V, Robert-Gangneux F. Alkyl galactofuranosides strongly interACTwith Leishmania donovani membrane and provide antileishmanial activity. Antimicrob Agents Chemother. 2014, 58:2156-2166 (IF 4.451)

Liu H, Charlier C, Defontaine A, Fateh A, Tellier C, Talham DR, Bujoli B. Design and optimization of a phosphopeptide anchor for specific immobilization of a capture protein on zirconium phosphonate modified supports. Langmuir. 2014, 30:13949‑55 (IF 4.187)


Teze D, Hendrickx J, Dion M, Tellier C, Woods VL, Tran V, Sanejouand Y-H. Conserved water molecules in family 1 glycosidases : a DXMS and molecular dynamics study. Biochemistry. 2013, 52:5900‑10 (IF 3.194)

Teze D, Dion M, Daligault F, Tran V, André-Miral C, Tellier C. Alkoxyamino glycoside acceptors for the regioselective synthesis of oligosaccharides using glycosynthases and transglycosidases. Bioorg Med Chem Lett. 2013, 23:448‑51 (IF 2.338)

Grandjean C, Wade TK, Ropartz D, Ernst L, Wade WF. Acid-detoxified Inaba lipopolysaccharide (pmLPS) is a superior cholera conjugate vaccine immunogen than hydrazine-detoxified lipopolysaccharide and induces vibriocidal and protective antibodies. Pathog Dis. 2013, 67:136‑58 (IF 2.554)

Arab-Jaziri F, Bissaro B, Dion M, Saurel O, Harrison D, Ferreira F, Milon A, Tellier C, Fauré R, O’Donohue MJ. Engineering transglycosidase activity into a GH51 α-l-arabinofuranosidase. New biotechnology. 2013, 30:536‑44 (IF 1.706)


Rigouin C, Delbarre-Ladrat C, Ratiskol J, Sinquin C, Colliec-Jouault S, Dion M. Screening of enzymatic activities for the depolymerisation of the marine bacterial exopolysaccharide HE800. Appl Microbiology Biot. 2012, 96:143‑51 (IF 3.689)

Muse M, Grandjean C, Wade TK, Wade WF. A one dose experimental cholera vaccine. FEMS Immunol Med Mic. 2012, 66:98‑115 (IF 2.684)

Milhomme O, Köhler SM, Ropartz D, Lesur D, Pilard S, Djedaïni-Pilard F, Beyer W, Grandjean C. Synthesis and immunochemical evaluation of a non-methylated disaccharide analogue of the anthrax tetrasaccharide. Org Biomol Chem. 2012, 10:8524–32 (IF 3.568)

Milhomme O, Dhénin SGY, Djedaïni-Pilard F, Moreau V, Grandjean C. Synthetic studies toward the anthrax tetrasaccharide : alternative synthesis of this antigen. Carbohydr Res. 2012, 356:115‑31
(IF 2.044)

Cinier M, Petit M, Pecorari F, Talham DR, Bujoli B, Tellier C. Engineering of a phosphorylatable tag for specific protein binding on zirconium phosphonate based microarrays. J Biol Inorg Chem. 2012, 17:399‑407 (IF 3.253)


Roy B, Ferdjani S, Tellier C, Rabiller C. Novel and convergent synthesis of modified glycosphingolipids, galactosyl-5-aza-sphinganines, by a diversity-oriented method. Tetrahedron. 2011, 67:5176‑83 (IF 2.803)

Miranda FF, Brient-Litzler E, Zidane N, Pecorari F, Bedouelle H. Reagentless fluorescent biosensors from artificial families of antigen binding proteins. Biosens Bioelectron. 2011, 26:4184‑90 (IF 5.437)

Ferdjani S, Ionita M, Roy B, Dion M, Djeghaba Z, Rabiller C, Tellier C. Correlation between thermostability and stability of glycosidases in ionic liquid. Biotechnol lett. 2011, 33:1215‑9 (IF 1.853)

Charrier T, Durand MJ, Jouanneau S, Dion M, Pernetti M, Poncelet D, Thouand G. A multi-channel bioluminescent bacterial biosensor for the on-line detection of metals and toxicity. Part I : design and optimization of bioluminescent bacterial strains. Anal Bioanal Chem. 2011, 400:1051-60 (IF 3.659)

Béhar G, Solé V, Defontaine A, Maillasson M, Quéméner A, Jacques Y, Tellier C. Evolution of interleukin-15 for higher E. coli expression and solubility. Protein Eng Des Sel. 2011, 24:283‑90 (IF 2.588)


Tran V, Hoffmann L, Rabiller C, Tellier C, Dion M. Rational design of a GH1 β-glycosidase to prevent self-condensation during the transglycosylation reaction. Protein Eng Des Sel. 2010, 23:43‑9 (IF 2.588)

Rahuel-Clermont S, Daligault F, Piet M-H, Gulberti S, Netter P, Branlant G, Magdalou J, Lattard V. Biochemical and thermodynamic characterization of mutated β1, 4- galactosyltransferase 7 involved in the progeroid form of the Ehlers- Danlos syndrome. Biochem J. 2010, 432:303-311 (IF 4.654)

Hajj HE, Abdelouas A, Grambow B, Martin C, Dion M. Microbial corrosion of P235GH steel under geological conditions. Phys Chem Earth. 2010, 35:248‑53 (IF 1.037)